Douglas Laboratories Pregnenolone 5 mg | Nutritional Supplement | Brain, Ovaries, Liver, Hormone Support* | 100 Tablets

Just ordered my second bottle of Pregnenolone. Here's why:When discovering the numerous symptoms (muscle loss, weight loss, fatique, brain fog, apathy, etc.) as a result of extreme stress, age (I'm a 68 year old woman), toxins, and Hashimoto's Thyroidism (new for me) and the return of Lupus (symptoms which had been gone for couple decades), I decided to determine what building blocks I needed to give my body to heal, instead of taking hormones (Thyroid, Testosterone) for the rest of my life as first suggested by my doctor. With additional labwork it was easy to determine what was needed. Urine had no detectable iodine. Selenium on the low side. T3 too low. Testosterone flat lined. Folate almost flat. Vitamin D3 at 18. These were the worse. So I started reading/research on hormones and Hashimoto's. Now taking appropriate vitamins and minerals, including iodine and selenium, and talking with my doctor, I began taking pregnenolone - 1/2 tablet a day, very gradually (like over weeks) building up to 2 tablets (10mg) every morning. I then added DHEA very gradually until now I take 1 tablet (5mg) every morning along with my iodine drops and selenium. At these dosages I feel alive, joy (which I did not know I had been missing for so long!), energetic, clear headed, motivated. It may also be helped by the B-complex I now take, or whatever. I know if I decrease the Pregnenolone and/or DHEA, I can feel the decrease in these qualities. I do know Hashimoto's is going into remission since body temperature and other symptoms have now consistently stabilized. And Lupus symptoms disappeared. In fact, even my 4 decade long arthritis disappeared. And I have some muscles! In a few months more labwork will be done to get true status to convince a doctor, but the results I am experiencing greatly satisfy me.Why Pregnenolone (and DHEA)?Pregnenolone is a precursor hormone. It is used by the body to make both stress and sex hormones. Pregnenolone MAKES Progesterone and DHEA., AND DHEA makes Testosterone (women need it if they want muscles to build and not waste away). In times of stress, the body diverts a lot of the pregnenolone toward stress hormone production (such as cortisol) and away from sex hormone production. This is a process called "Pregnenolone Steal" where Pregnenolone is used by the body to create more of the cortisol hormone to deal with the stress and thus is less available for the other hormones. The answer is to reduce/manage stress to lessen need of cortisol and have more pregnenolone to build other hormones.DHEA reduces the production of autoantibodies, which obviously I need since I am dealing with two autoimmune diseases. I know that as we age, we produce less DHEA (as well as pregnenolone), so a major stressful event most certainly jeapordizes a Senior's health/life.

In reality, I didn't quite know what to expect. I'm always on the hunt for products that reduce generalized anxiety without making me feel out of it or lethargic, and I am rarely impressed. However, I was actually rather surprised when that is exactly what this did. After about an hour or so (maybe less) I start feeling energetic and happy. I want to hang out with friends and family, and when I do I'm much more conversational and engaging. I bought this hoping for a gentle push in that direction, but this exceeded my expectations.I've taken both full and half-tablet doses both once and twice a day, and I've even had several days where I didn't take it at all. I have to say I've noticed quite a difference in my mood and energy level on those days. I take other supplements, as well, so there might be synergistic effect happening, but this product definitely makes a difference on the days I take it.As far as taking it, I go with the sublingual option (letting it dissolve under the tongue), since that is what my research has shown to be the most effective. In that regard, it dissolves within several minutes and has a pleasant enough taste. Don't get it me wrong, it doesn't taste good, it's more that it's good in an ignorable, flavorless kind of way.Overall, I've seen definite results and I will be reordering when this bottle is done.

Wow, just wow. That's about all I can say. Pregnenolone has been my magic bullet in middle age.As I hit the middle years, I've known that something wasn't quite right ... foggy thinking, weight gain, poor sleep, and on & on. If you're reading this, it's possible you've been experiencing that as well. I simply decided that I would not accept it as a "natural" part of aging or peri-menopause. So I began my journey to resolve this ... two year ago.After 2 years of working through all kinds of alternative medicine & therapies, including HRT, biofeedback and acupuncture, it was low-dose pregnenolone (coupled with progesterone cream and occasionally DHEA cream) that was the difference maker for me. I've spent well over 4 figures in & out of doctor's offices and on blood tests, stool tests, you name it. But no one ... and I mean NO ONE ... tapped into what was going on for me, which basically was estrogen dominance (hence, progesterone) and cortisol issues. So, I went on my own quest and tried pregnenolone, among a few other things.What I learned was that too much of a good thing is a bad thing. I initially tried 25mg and it was just too much. As I did more research, I decided sublingual administration was likely better. I take only 1/2 tab (2.5 mg) daily. That's it. It is just enough to help balance me. I realize I might have to adjust again at some time but having done that before, I know I can do it again.Regardless, I can not reiterate how important eating well, exercising, and having a happy home & enjoyable work are to your well-being. However, for those of us who need a little help beyond that -- and many of us do -- don't overlook the importance of steroids & hormones as a part of healthy aging. I'm so glad that I didn't.

La medicina es muy buena pero nunca me llegó cuánto lo siento es lo q tomo porq soy asmática

I am taking 5 mg daily. Haven’t seen a big difference, but it’s a very low dose. Haven’t been taking it that long

I have used this Douglas brand multiple times and comparison to tablet forms and found that this product seems to sit better in my stomach. I should’ve noticed that I purchased tablets, but at the time this brand was out of stock and I needed to purchase something before travel. I would buy this brand again, even though it cost more than a few of the others.