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💡 Elevate your heart and mind with the folate formula designed for peak performance
Life Extension High Potency Optimized Folate delivers a powerful 8500 mcg dose of 5-MTHF, the bioactive form of folate that bypasses common genetic conversion issues. This supplement supports cardiovascular health by maintaining normal homocysteine levels and promotes cognitive wellness. Crafted with non-GMO, gluten-free, and vegetarian ingredients, it’s a science-driven choice for professionals seeking optimized brain and heart support.










| ASIN | B00V756QFK |
| Age Range Description | Adult |
| Allergen Information | Gluten Free |
| Best Sellers Rank | #24,228 in Health & Household ( See Top 100 in Health & Household ) #31 in Vitamin B9 (Folic Acid) Supplements |
| Brand | Life Extension |
| Brand Name | Life Extension |
| Color | Off White |
| Container Type | Bottle |
| Customer Reviews | 4.6 out of 5 stars 571 Reviews |
| Diet Type | Vegetarian |
| Dosage Form | Tablet |
| Flavor | Unflavored |
| Global Trade Identification Number | 00737870191339 |
| Item Dimensions | 2.09 x 2.09 x 3.73 inches |
| Item Form | Tablet |
| Item Highlight | L-Methylfolate & Folic Acid for Heart & Brain Support, Healthy Homocysteine Levels, Gluten-Free, Non-GMO & Vegetarian |
| Item Nype Name | L-Methylfolate Supplement |
| Item Weight | 1.12 ounces |
| Manufacturer | Life Extension |
| Manufacturer Part Number | 01913 |
| Material Type Free | Gluten Free |
| Model Name | Life Extension High Potency Optimized Folate |
| Model Number | 01913 |
| Number of Items | 1 |
| Primary Supplement Type | Folate [as (6S)-5-Methyltetrahydrofolate, calcium salt] |
| Product Benefits | Heart Health Supplements, Brain Health Supplements |
| Special Ingredients | Folate [as (6S)-5-Methyltetrahydrofolate, calcium salt] |
| Specific Uses For Product | Heart Health Supplements, Brain Health Supplements |
| UPC | 737870191339 |
| Unit Count | 30 Count |
E**B
Delayed release effect compared to a quicker releasing 'capsule' form.
I have done a couple other reviews on l-methyl folate supplements, and I can't really repeat everything I've said, but perhaps you could look them up under my reviewer name, I'm not sure. I'll just give you the main points I made in the other reviews: And this is just my layman's advice, from the limited experience I have with the supplement and the knowledge I've gained reading about it online and from my sister, who has been taking it for over a year now. First of all, you should probably get the genetic testing done to see if you have the MTHFR mutation in the first place. That is where my sister started, and because of the results, her naturopath suggested she started taking this stuff. If you do start taking it, START WITH A LOW DOSE, and work your way up. I assumed I had the mutation, because of my sister's genetic test results she was told that both of her parents must have the mutation, and therefore all of her siblings will have it too. I decided on my own to just start with a high dose of 15mg, and I didn't have good results. It made me feel more anxious, irritated, and antsy. I dropped down to this lower dose, and still didn't feel 'right' after taking it. I then tried half, so about 4mg, and at that point I might have felt something, but for the most part I didn't feel that it really changed my life in a noticeable way, so now I don't take it at all. Either way, I recommend, and all the info I found online says the same thing, to start with a low dose, like 1mg, and then over weeks and months, and with the support of a healthcare professional of some sort, work your way up slowly until you find the right dose for you. With all that said, I can also tell you that one of my other siblings, who has had some pretty extreme mental health issues to say the least, has started taking these supplements, along with eating fish a few times a week (before they had been a vegetarian for like 20 years...), and the combination of the two things seems to REALLY effect their mental state. I can literally tell when they have run out of the supplements, their mood and attitude is so different. (I'm using they/their to try to keep it more private, as I have multiple siblings...) Good luck, I know that one day the whole 'medical field' will catch up with all this mental health and genetic testing stuff but until then we just have to try to figure out what works best for us. And the other thing I pointed out in my other reviews is that besides any supplements you might take, I think that developing consistent and healthy habits is the best thing we can do to foster a stable mental state-The basic stuff like sleep, diet, exercise, stress management, and our alcohol/drug use.
M**H
The only vitamins ANYONE should take!
This vitamin is the only vitamin anyone should take daily. As it is in its most natural forms which allows the body to fully absorb it all! It's small and easy to swallow and to say I can see a difference would be an understatement! the energy levels I have are out the roof! The pull is little so it’s easy to swallow and only has a taste if you let it dissolve in your mouth. The price is average but worth it due to how well they work!
E**A
Reconocedor, de la calidad.
lo hemos comprados en varias ocaciones, son originales.
C**N
Great product
Great for moods, energy, no after taste great value for the money.
D**H
I tried many brands, I feel this one actually works.
It's kind of hard to run these kinds of experiments on yourself because there are so many variables about your body and what you put into it. But I am reasonably sure these are the most legit Folate pills I've tried on the amazon market as a substitute for Deplin which is too pricey. I tried about 4 other brands and thought they didn't do much for the way I felt. One difference right up front is these are actual pills whereas all the other ones were capsules with powder inside. I don't know too much about pharmacology but I do know if I were a sketchy amateur supplement manufacturer I can stuff a capsule with stuff whereas I don't know how to make a pill. So if all the other ones are sketchy, I want to make sure I support this product. I hope the price stays the same or maybe even goes lower. Hope this review helps.
R**.
Helps shut down ADHD for sleep
Helps my husband with ADHD get to sleep more quickly. Daytime use made him a little sleepy, so suggest a half dose for daytime
I**S
Works great!!
Easy to swallow works great!!
M**S
The packaging …
Makes me wonder about all those voices screaming “environmental blah, blah” and I’m like I just want less bulk, waste of so many resources, and don’t want to imagine the landfills because recycling isn’t a thing since COVID. Yes there is actually 30 tablets that can’t even cover the bottom 😂 and I threw the HUGE piece of cotton in the jar away that protects the pills from all that space. I’ll update once I’ve had time to get over this much package exaggeration and have had time to try the product. Pretty bottle package though. Gave five stars because I hate to see the complaint that has nothing to do with the actual product affect the rating.
A**G
So toma cuidado com a dosagem exessiva, e muito forte.
E o melhor !
W**N
Great service and great concentration at a good price..
My package arrived on time and was exactly as described. Also As far as I can see this is the highest concentration of Methyl Folate (5000 mcgs) available online. Thanks very much.
A**A
جيد
جيد
Trustpilot
1 month ago
3 days ago